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The Most Important Medical Discovery in the Last 50 Years

"...apoptosis in chronic heart failure is mediated in part by telomere dysfunction and suggest an essential role for TRF2 even in postmitotic cells."

Oh H., et al. Proceedings of the National Academy of Science, 2003, 10.1073

Okay, maybe not. It's pretty well-known that telomere deterioration plays a role in cell aging and death, so it's not a big stretch to say that telomere repeat-binding factors play a role in protecting cardiomyocytes from various stress factors. On the other hand, there's a whole lot of shit-shoveling involved between a simple theory and a published paper.